Manager Clinical Pharmacology (4691010)
Full-time, Cambridge, MA
Pfizer Clinical Pharmacology has an open position as Clinical Pharmacology Lead in Early Clinical Development. The ideal candidate embraces model-based drug development - constructs, validates, and utilizes disease, placebo, exposure-response, and mechanistic PKPD models to evaluate risk/benefit and facilitate drug development decisions, in close collaboration with other R&D partners. Clinical Pharmacology Leads are also responsible for planning and direction of clinical pharmacology components of clinical programs (including clinical development plan/life cycle plan) and studies (including protocol preparation; clinical phase oversight, and reporting).
Pfizer is a leader in Model-based Drug Development, and we are expanding its influence in target validation and selection. Pfizer Clinical Pharmacology Leads have key roles to play in influencing the discovery and development of drugs. It is exciting, critical work and you could be part of it. The main responsibilities include PK-PD analysis, collaboration with Clinical Sub Team and Development as Clinical Pharmacology representatives, implementation of model-based development, participation in clinical pharmacology components of Clinical Plans.
• PhD in Clinical Pharmacology, Pharmacokinetics, Pharmacometrics, Engineering or other
suitable post-graduate qualification
• 0-3 years of industry or equivalent experience in clinical pharmacology and/or clinical PK/PD and/or pharmacometrics
Strong quantitative skills and expertise (e.g. experience in mechanistic PKPD modeling/systems
pharmacology, literature meta-analyses, population modeling, and clinical trial simulations)
• Excellent written and verbal communication skills
• Demonstrated presentation skills